Bioluminescence is the process of creating biological light within the cell as a result of a chemical reaction in living organisms. In addition to being a visual feast in nature, the change in the amount of biological light created against various agents also leads to the formation of many application areas in terms of biotechnology. One of the areas where the application is carried out is marine ecosystems. Because the negative consequences of the increasing human population are the increase in pollutants from both industrial and anthropogenic sources. For this reason, in such habitats, it is necessary to detect pollutants with environmentally friendly, easy-to- apply, repeatable and sensitive bioassays and to take both pollution prevention and pollution removal measures. Considering the increasing environmental pollution, it is necessary to regularly perform biomonitoring in all ecosystems with innovative technologies, with the awareness that the earth can be without us but we cannot be without the earth.