Abstract This article discusses the development of IgY technologies for the treatment and prevention of infectious diseases in dogs, such as parvovirus enteritis, distemper and hepatitis. These diseases are a significant threat to canine health and they are highly lethal, that emphasizing the need for new, effective and safe agents. Methods for isolating, purifying and determining the concentration of IgY immunoglobulins from egg yolks of hyperimmunized chickens are described. Clinical tests on dogs to determine the efficacy of the resulting preparation were also performed. During the study it was found that the IgY-based product significantly improves the immune response in dogs, helps to reduce the severity of the parvovirus enteritis, canine distemper, and infectious hepatitis and accelerates the dog's recovery by 2 days (20-28%). Potential advantages of the new drug in comparison with existing therapeutic agents, as well as its possible application in veterinary practice are discussed. The proposed IgY-based drug is a prospective tool for the treatment and prevention of serious infectious diseases in dogs, which opens up new opportunities in the field of veterinary medicine.