Based on experimental values of dynamic viscosity and density of n-amyl alcohol in the pressure range of 11.09 MPa-49.14 MPa and temperature range of 288.95 K-567.35 K the activation Gibbs energy of viscous flow, the activation enthalpy of viscous flow, the activation entropy of viscous flow, the isobaric expansion coefficient and the isothermal compression coefficient were calculated and the changes of these parameters depending on temperature and pressure were analyzed. It was determined that with the increase in temperature at a given pressure, the activation Gibbs energy of viscous flow first decreases and then increases, the activation enthalpy of viscous flow and the activation of entropy of viscous flow only decrease, and the isobaric expansion coefficient and isothermal compression coefficient only increase.